Duplex

Ben Stiller

Alex Rose

Drew Barrymore

Nancy Kendricks

Eileen Essell

Mrs. Connelly

Harvey Fierstein

Kenneth

Justin Theroux

Coop

James Remar

Chick

Robert Wisdom

Officer Dan

Swoosie Kurtz

Jean

Wallace Shawn

Herman

Maya Rudolph

Tara

Amber Valletta

Celine

Cheryl Bartel

Ginger

Tim Maculan

Terrence

Jackie Sandler

Bartender

Evgeniy Lazarev

Mr. Dzerzhinsky

Kumar Pallana

Indian Restaurant Owner

Philip Perlman

Phil

Gary Riotto

Drug Dealer

Michelle Krusiec

Dr. Kang

Margie Loomis

Old Biddy

Linda Porter

Old Biddy

Edward Edwards

Antique Dealer

Louis Giambalvo

Pharmacist

Tracey Walter

Pharmacy Customer

John Hamburg

Mr. Friedman

Christina Kirk

Mrs. Friedman

Jenette Goldstein

Moderator

Leyna Nguyen

Newscaster

Chuma Gault

Mailroom Guy

Jim Castillo

Weatherman

Michael Fahn

Sneezer on Train

Roberta R. Deen

Caterer

Christopher Doyle

Tavern Bartender

Christine La Fontaine

Don Piper Fan

Joey Banks

Police Officer

Geraldine Hughes

Receptionist

Picasso

Little Dick

Guiles

Little Dick

Bugsy

Little Dick

Maestro

Little Dick

Will Blomquist

College Student on Subway (uncredited)

Danny DeVito

Narrator (voice) (uncredited)

Azizah Rowen

Barista (uncredited)

Larry Vigus

Man on Street (uncredited)